ఆండ్రాలజీ & గైనకాలజీ: ప్రస్తుత పరిశోధన

Spatial Arrangement of the Microvascular Bed in the Human Placenta

Marie Jirkovsk?

Spatial Arrangement of the Microvascular Bed in the Human Placenta

The knowledge of the spatial arrangement of microvascular bed is necessary for understanding the organ function. Various models and functional interpretations of the spatial organization of placental microvascular bed were created in the past decades however their plausibility was highly influenced by technical level of used methods. In this paper, methods and results of those studies are summarized and discussed. As the placenta in utero is hardly accessible for examination, the data regarding spatial arrangement of microvascular bed were obtained from ex vivo studies after termination of pregnancy. Imaging methods, i.e. X-ray angiography, X-ray microcomputed tomography and nowadays also MRI yielded information mainly on the spatial distribution and quantitative parameters of placental arterial system. The combination of SEM and corrosion casts demonstrated that capillaries of terminal villi branch from arterioles of mature intermediate villi, some capillary segments interconnect the capillary bed of neighboring terminal villi, and venules are arranged parallel with arterioles of mature terminal villi.