W.E. Feeman, Jr
LDL Lowering: Evidence for a Plaque Non-Progression Threshold
The holy grail of Interventional Lipidology is the prevention of the cholesterol-rich plaque, which is the basis, along with thrombosis, of atherothrombotic disease (ATD), or if the cholesterol-rich plaque is extant, then stabilization/regression of that plaque, in the hope of preventing subsequent ATD events. The prediction of the population at risk of ATD is the bedrock upon which the prevention of ATD is based. Fortunately, the population at risk of ATD is readily and accurately predictable, so that the prevention of ATD is possible.